EORTC-NCI-AACR Symposium 2016 poster: Preliminary Phase 1 results of PTC596, a novel small molecule targeting cancer stem cells (CSCs) by reducing levels of BMI1 protein

The study design and results of a Phase 1 clinical trial investigating PTC596 in a range of solid tumors are presented in our poster at the 2016 EORTC-NCI-AACR Symposium in Munich 

  • Findings from a trial investigating PTC596, a novel, oral compound, which reduces survival of treatment-resistant CSCs by lowering BMI1 protein levels, are presented
  • Results from 28 patients with solid tumors treated with PTC596 in this dose-escalation study are shown, including tumor response, pharmacokinetic profiles, and safety/tolerability data
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