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Home | Central nervous system | Aromatic L-amino acid decarboxylase (AADC) deficiency | Congress activities | The American College of Medical Genetics (ACMG) | ACMG 2025 oral presentation: Administration of eladocagene exuparvovec using the SmartFlow magnetic resonance-compatible ventricular cannula in pediatric patients with aromatic L-amino acid decarboxylase deficiency

ACMG 2025 oral presentation: Administration of eladocagene exuparvovec using the SmartFlow magnetic resonance-compatible ventricular cannula in pediatric patients with aromatic L-amino acid decarboxylase deficiency

This oral presentation, presented at ACMG 2025, assesses the pharmacodynamics of eladocagene exuparvovec using the SmartFlow magnetic resonance (MR)-compatible ventricular cannula in pediatric patients with aromatic L-amino acid decarboxylase (AADC) deficiency

  • Understand the SmartFlow MR-compatible ventricular cannula for intraputaminal administration
  • Review the pharmacodynamics of eladocagene exuparvovec through cerebrospinal fluid homovanillic acid levels and putaminal-specific [18F] fluorodopa uptake in patients with AADC deficiency
  • Learn about the safety of bilateral intraputaminal infusion of eladocagene exuparvovec in pediatric patients
Always consult the prescribing information before prescribing any products

MED-US-CORP-2500008 | November 2025

This poster was developed and funded by PTC Therapeutics for ACMG 2025.

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