Publication: AAV2-hAADC (eladocagene exuparvovec) biodistribution and expression: Superiority of intraputaminal versus intracerebroventricular and intrathecal (lumbar) routes of administration
This research article, published in the International Journal of Toxicology, assesses alternative routes of human aromatic L-amino acid decarboxylase (hAADC) enzyme administration in monkeys by evaluating its biodistribution and expression
- Learn about minimally invasive dosing options using intraputaminal, intracerebroventricular, and intrathecal administration
- Compare how the routes for administration affect transgene levels in the central nervous system
MED-US-CORP-2500008 | November 2025
Compton DR, DeMarco SJ, Yalamanchili P. Int J Toxicol. 2023;42(2):135–145
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MED-US-CORP-2600001 | February 2026
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