Home | Metabolism | Phenylketonuria (PKU) | Publications | Publication: Effects of oral sepiapterin on blood Phe concentration in a broad range of patients with phenylketonuria (APHENITY): Results of an international, phase 3, randomised, double-blind, placebo-controlled trial
Publication: Effects of oral sepiapterin on blood Phe concentration in a broad range of patients with phenylketonuria (APHENITY): Results of an international, phase 3, randomised, double-blind, placebo-controlled trial
Published in The Lancet 2024, this research article presents findings from APHENITY, a Phase 3 clinical trial evaluating the efficacy and safety of sepiapterin in patients with phenylketonuria (PKU)
Understand the clinical efficacy of sepiapterin in patients with PKU
Review the effect of sepiapterin on blood phenylalanine (Phe) in participants who completed the Phase 3 APHENITY trial
Learn more about the safety profile of sepiapterin in this study
Muntau A, Longo N, Ezgu F, et al. Lancet 2024; 404:1333–45
Sepiapterin is an investigational product and is not currently approved in any country.
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MED-ALL-PKU-2400226 | October 2024
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