Home | Neuromuscular | Duchenne muscular dystrophy (DMD) | Publications | Publication: Deflazacort vs prednisone treatment for Duchenne muscular dystrophy (DMD): A meta-analysis of disease progression rates in recent multicenter clinical trials

Publication: Deflazacort vs prednisone treatment for Duchenne muscular dystrophy (DMD): A meta-analysis of disease progression rates in recent multicenter clinical trials

This clinical research article, published in the Muscle & Nerve Journal, compares disease progression among boys enrolled in the placebo arms of 2 DMD clinical trials receiving deflazacort or prednisone/prednisolone

Review the outcomes of a post hoc meta-analysis of deflazacort and prednisone in DMD patients receiving placebo in 2 independent phase 3 trials
The primary functional outcomes reflecting measures of disease progression over 48 weeks are discussed

PTC Therapeutics is the Marketing Authorization Holder for deflazacort in the US only. Registration conditions differ internationally, and prescribing information may vary depending on local approval in each country. The US Prescribing Information for deflazacort is available here. Please refer to your local country guidance for more information.

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MED-ALL-DFZ-2500002 | March 2025

McDonald CM, Sajeev G, Yao Z, et al. Muscle Nerve. 2020;61:26–35

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MED-ALL-DMD-2200190 | June 2025

Publication: Deflazacort vs prednisone treatment for Duchenne muscular dystrophy (DMD): A meta-analysis of disease progression rates in recent multicenter clinical trials

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