Publication: Comparing deflazacort and prednisone in Duchenne muscular dystrophy

This paper, published in the Journal of Neuromuscular Diseases, explores the key similarities and differences between 2 corticosteroid treatments and their effectiveness when used in patients with Duchenne muscular dystrophy (DMD)

Compare key pharmacological features of deflazacort and prednisone, including mechanism of action, efficacy, and safety
Explore further differentiating features such as lipid solubility, pharmacokinetics, changes in gene expression profiles, and impact on glucose metabolism
Review a summary of data from clinical trials, prospective studies, meta-analyses, and post hoc analyses

Biggar WD, Skalsky A, McDonald CM. J Neuromuscul Dis. 2022;9(4):463–476

Deflazacort is a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients 2 years of age and older. PTC Therapeutics is the Marketing Authorization Holder for deflazacort in the US only. Registration conditions differ internationally, and prescribing information may vary depending on local approval in each country. The US Prescribing Information for deflazacort is available here. Please refer to your local country guidance for more information.

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Publication: Comparing deflazacort and prednisone in Duchenne muscular dystrophy

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