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Publication: In vitro metabolism, reaction phenotyping, enzyme kinetics, CYP inhibition and induction potential of ataluren

This research article, published in Pharmacology Research and Perspectives, describes the in vitro metabolism and enzyme kinetics of ataluren and its interaction with CYP enzymes 

  • The disposition and metabolism of ataluren in vitro is described
  • The data relating to the enzyme kinetics of ataluren and its interaction with CYP enzymes is presented

Kong R, Ma J, Hwang S, et al. Pharmacol Res Perspect. 2020;8(2):e00576 

▼ Ataluren is subject to additional monitoring. This will allow quick identification of new safety information. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system. Adverse events should also be reported to PTC at pharmacovigilance@ptcbio.com.

Registration conditions differ internationally, and prescribing information may vary depending on local approval in each country. The European Summary of Product Characteristics for ataluren is available here. Please refer to your local country guidance for more information. 

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