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Home | Neuromuscular | Duchenne muscular dystrophy (DMD) | Publications | Publication: In vitro metabolism, reaction phenotyping, enzyme kinetics, CYP inhibition and induction potential of ataluren

Publication: In vitro metabolism, reaction phenotyping, enzyme kinetics, CYP inhibition and induction potential of ataluren

This research article, published in Pharmacology Research and Perspectives, describes the in vitro metabolism and enzyme kinetics of ataluren and its interaction with CYP enzymes

  • The disposition and metabolism of ataluren in vitro is described
  • The data relating to the enzyme kinetics of ataluren and its interaction with CYP enzymes is presented
▼ Ataluren is subject to additional monitoring. This will allow quick identification of new safety information. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system. Adverse events should also be reported to PTC Therapeutics at pharmacovigilance@ptcbio.com.

Registration conditions differ internationally; always consult local prescribing information and/or Summary of Product Characteristics before prescribing any products.

MED-ALL-ATLN-2500006 | September 2025

Kong R, Ma J, Hwang S, et al. Pharmacol Res Perspect. 2020;8(2):e00576

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MED-ALL-DMD-2300008 | June 2025

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